The Moore Lab focuses on understanding how metabolic stressors drive chronic inflammatory responses and cardiovascular disease

The Moore Lab at NYU focuses on identifying molecular mechanisms that underpin metabolic dysregulation and chronic inflammation in cardiometabolic diseases. Our studies integrate basic discovery, preclinical and translational research in the areas of noncoding RNA biology, innate immunity and lipid metabolism.

The lab is led by Kathryn Moore, the Jean and David Blechman Professor of Cardiology, Professor of Cell Biology, and the Director of the NYU Cardiovascular Research Center.

What's New?

Key Recent Publications

Featured
Long noncoding RNA CHROMR regulates antiviral immunity in humans
Long noncoding RNA CHROMR regulates antiviral immunity in humans

van Solingen, C, Cyr, Y, Scacalossi, K et al. (2022). PNAS.

miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques
miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques

Afonso MS, Sharma M, Schlegel M, van Solingen C, Koelwyn GJ, Shanley LC, Beckett L, Peled D, Rahman K, Giannarelli C, Li H, Brown EJ, Khodadadi-Jamayran A, Fisher EA and Moore KJ. (2021). Circ Res.

Myocardial infarction accelerates breast cancer via innate immune reprogramming
Myocardial infarction accelerates breast cancer via innate immune reprogramming

Koelwyn, GJ, Newman, AAC, Afonso, MS, et al. (2020). Nature Medicine, 26, 1452–1458.

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