People
Kathryn J Moore, PhD, FAHA
Dr. Kathryn Moore is the Jean and David Blechman Professor of Cardiology, and the Director of the Cardiovascular Research Center at New York University’s Grossman School of Medicine. She is internationally recognized for her research on the molecular pathogenesis of cardiometabolic diseases, and the roles that non-coding RNAs and dysregulated immune responses play in those settings. By forging new links between lipids, metabolism and innate immunity, her discoveries have revealed fundamental insights into pathways that regulate cholesterol homeostasis and vascular inflammation.
Dr. Moore received her B.Sc. (Microbiology) and Ph.D. (Parasitology/Immunology) degrees from McGill University in Montreal, Canada. Although her early research focused on the immune response to pathogens, Dr. Moore became fascinated with the mechanisms of “sterile” inflammation in disease, and pursued her postdoctoral training at Harvard Medical School, focusing on the mechanisms of chronic inflammation in lupus (Brigham and Women’s Hospital) and atherosclerotic cardiovascular disease (Massachusetts General Hospital). She joined the faculty at Harvard Medical School and Massachusetts General Hospital in 2001 as an Assistant Professor in the Department of Medicine, with secondary faculty appointments in the Center for Human Genetic Research, and the Center for Study of Inflammatory Bowel Disease. In 2009, Dr. Moore was recruited to New York University School of Medicine, where she is a tenured professor in the departments of Medicine and Cell Biology. In 2019, she established the NYULH Cardiovascular Research Center that fosters cross-disciplinary research in basic, translational and clinical cardiovascular sciences.
Dr. Moore’s contributions to the fields of innate immunity and vascular biology have been recognized by numerous awards and honors, including among others, the NIH’s Outstanding Investigator Award, Clarion’s List of Most Highly Cited Researchers (top 1%), the American Heart Association’s Distinguished Scientist Award, the Gill Heart and Vascular Institute Award for Outstanding Contributions to Cardiovascular Research, and election to the National Academy of Sciences USA, among others.
Dr. Moore is an active volunteer for the American Heart Association, and served on the Leadership Committee of the Arteriosclerosis, Thrombosis and Vascular Biology Council from 2004-18, including as Chair of the Council from 2014-2016. During her tenure on the Committee, Dr. Moore made mentoring the next generation of scientists a top priority and helped to develop recommendations for AHA policies in the areas of science and medicine. Dr. Moore is Deputy Editor of the Circulation Research journal, and serves on multiple scientific advisory boards, including the NYULH Colton Center for Autoimmunity and Beren Therapeutics.
Research Assistant Professor
Coen van Solingen
PhD, Leiden University, Netherlands, 2012
Coen is exploring the role of non-coding RNAs in vascular biology and lipid metabolism.
Postdoctoral Fellows
Morgane Gourvest
PhD, Paul Sabatier University, France, 2020
Morgane aims to uncover how the dysregulation of long noncoding RNAs (lncRNAs) contribute to cardiovascular diseases by combining high-throughput genomics, genetically engineered animal models and human cellular systems.
José Gabriel B Durán
PhD, Weill Cornell School of Medicine, 2019
Gabriel carried out basic science research in the fields of vascular and stem cell biology, hematopoiesis, and reprogramming. At the Moore Lab, he is focusing on more translational work, using computational tools to understand the immune cell landscape of atherosclerotic plaques. His goal is to harness this knowledge and design testable approaches to achieve plaque regression.
Alexandra Newman
PhD, University of Virginia, 2019
Alexandra is a vascular biologist studying the effects MI and cancer, focusing on ischemia-induced changes within the pre-metastatic niche in the lung.
Yannick Cyr
PhD, University of Montreal, 2020
Yannick is investigating the role of molecular guidance cues in the development of metabolic diseases.
Graduate Students
Kristin Wang
PhD Student
Kristin studies the role of RNA granules in cardiovascular disease. Recently, our group identified stress granules (SGs) in macrophages and smooth muscle cells in murine atherosclerotic plaques. Inhibition of SG assembly led to increased expression of the anti-inflammatory cytokine, IL-4. Her project aims to elucidate the mechanism by which macrophage uptake of lipoproteins induces the formation of SGs that sequester proteins and RNA, thereby influencing post-transcriptional regulation and atherosclerotic disease progression.
Fazli Bozal
MD/PhD Student
Fazli works on two aspects of cardiovascular disease. First, the immunometabolic regulation of immune cells and resolution of inflammation within the atherosclerotic plaque. Second, innate immune reprogramming following myocardial infarction.
Richard Von Itter
PhD Student
Richard is studying how cardiovascular disease influences systemic inflammation, immunity, and metabolism to exacerbate cancer progression.
Lab Staff
Gabrielle Pilla
Research Associate
Tracy Zhang
Research Associate
Samantha Dupuis
Research Technician
Maia Livneh
Research Associate
Alumni
Brian Lim
2020-2021
Integrated Thoracic Surgery Resident, Cedars-Sinai Medical Center
Graeme Koelwyn
2014-2020
Assistant Professor in the Faculty of Health Sciences, Simon Fraser University and the in Public Health ‘Omics in Exercise and Disease, St Paul’s Hospital
Milessa Afonso
2016-2020
Research Scientist, Gilead Sciences Inflammation & Fibrosis Department
Danny Peled
2018-2020
Medical Student, Technion Israel Institute of Technology
Paul Martin Schlegel
2017-2019
Assistant Professor, University of Munich
Monika Sharma
2017-2019
Research Scientist, Gilead Pharmaceutical
Emma Corr
2017-2019
Clinical Scientific Expert, Novartis
Kaitlyn Scacalossi
2014-2017
Manager of Clinical Publications and Medical affairs, Regeneron
Mireille Ouimet
2011-2016
Assistant Professor and Director of the Cardiovascular Metabolism and Cell Biology Laboratory, University of Ottawa Heart Institute
Bhama Ramkhelawon
2011-2016
Assistant Professor and Director of Vascular Surgery Scientific Research, New York University Grossman School of Medicine
Elizabeth J Hennessy
2011-2013
Senior Research Investigator, University of Pennsylvania Institute for Translational Medicine and Therapeutics
Frederick J Sheedy
2010-2013
Associate Professor, Trinity College Dublin
Katey Rayner
2009-2012
Professor, Research Chair in Vascular & Metabolic Inflammation and Assistant Dean of Research and Special Projects, University of Ottawa Heart Institute